End-to-End Optimization of High-Throughput DNA Sequencing
نویسندگان
چکیده
منابع مشابه
End-to-End Optimization of High-Throughput DNA Sequencing
At the core of Illumina's high-throughput DNA sequencing platforms lies a biophysical surface process that results in a random geometry of clusters of homogeneous short DNA fragments typically hundreds of base pairs long-bridge amplification. The statistical properties of this random process and the lengths of the fragments are critical as they affect the information that can be subsequently ex...
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ژورنال
عنوان ژورنال: Journal of Computational Biology
سال: 2016
ISSN: 1066-5277,1557-8666
DOI: 10.1089/cmb.2015.0185